Crossword Genius

Know-it-all lives in care we suspect (8)

Ross

I believe the answer is:

wiseacre

'know-it-all' is the definition.
(I've seen this before)

'lives in care we suspect' is the wordplay.
'lives' becomes 'is' ('be' can be a synonym of 'live').
'in' indicates putting letters inside.
'suspect' indicates an anagram.
'care'+'we'='carewe'
'carewe' anagrammed gives 'weacre'.
'is' placed inside 'weacre' is 'WISEACRE'.

(Other definitions for wiseacre that I've seen before include "Person with an affectation of wisdom" , "Smart alec" , "Smart Aleck" , "Person who tries to appear clever" , "Self-appointed sage" .)

I've seen this clue in The Independent.
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