Lake into which the Cuyahoga empties (4)
I believe the answer is:
erie
'lake into which the cuyahoga empties' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for erie that I've seen before include "Superior companion" , "Great lake in Eire" , "North american lake sounds spooky" , "A Great American lake - sounds spooky" , "Buffalo's lake" .)