Large part of Asia ignoring small part of Europe (6)
I believe the answer is:
iberia
'part of europe' is the definition.
(peninsula including Spain and Portugal)
'large part of asia ignoring small' is the wordplay.
'large part of asia' becomes 'Siberia'.
'ignoring' suggests deleting specific letters.
'small' becomes 's' (abbreviation - e.g. clothes size).
'siberia' with 's' removed is 'IBERIA'.
(Other definitions for iberia that I've seen before include "Old name for Spanish peninsula" , "It comprises Spain and Portugal" , "Where Juan possibly lives" , "Great European peninsula containing Spain and Portugal" , "Spain's national flag-carrying airline" .)