Crossword Genius

Last couple escaping death in Great Plague (8)

Ross

I believe the answer is:

epidemic

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'plague' is the definition.
(I've seen this before)

I can't explain the rest of the clue.

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(Other definitions for epidemic that I've seen before include "Dim piece (anag)" , "Widespread occurrence of a disease" , "Unfortunately widespread" , "Rash" , "medical emergency" .)

I've seen this clue in The Times and The Sun.
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