Leader in government has moved to the slum area (6)
I believe the answer is:
ghetto
'slum area' is the definition.
(I've seen this before)
'leader in government has moved to the' is the wordplay.
'leader in' indicates taking the first letters.
'has' is a charade indicator (letters next to each other).
'moved' indicates an anagram.
The first letter of 'government' is 'g'.
'to'+'the'='tothe'
'tothe' with letters rearranged gives 'hetto'.
'g'+'hetto'='GHETTO'
(Other definitions for ghetto that I've seen before include "Segregated part of city for minority" , "Area for those deprived" , "Densely populated city slum" , "run-down part of town" , "poor part of town" .)