Little one originally trained in technology can’t handle (5)
I believe the answer is:
titch
'little one' is the definition.
(I've seen this before)
'originally trained in technology can't handle' is the wordplay.
'originally' says to take the initial letters.
The first letters of 'trained in technology cant handle' is 'TITCH'.
(Other definitions for titch that I've seen before include "Small man (colloq.)" , "small one" , "Little one" , "One's very short" , "Short person" .)