Live and prosper, lacking nothing (5)
I believe the answer is:
dwell
'live' is the definition.
(to live/dwell somewhere)
'prosper lacking nothing' is the wordplay.
'prosper' becomes 'dowell' (I've seen this in another clue).
'lacking' indicates named letters should be taken away.
'nothing' becomes 'O' (looks like zero - 0).
'dowell' with 'o' taken away is 'DWELL'.
'and' acts as a link.
(Other definitions for dwell that I've seen before include "Exist (within)" , "Harp" , "Inhabit" , "Abide, reside" , "Settle" .)