Live with head of department in good health (5)
I believe the answer is:
dwell
'live' is the definition.
(I know that live can be written as dwell)
'head of department in good health' is the wordplay.
'head of' indicates taking the first letters.
'in good health' becomes 'well' (similar in meaning).
The initial letter of 'department' is 'd'.
'd'+'well'='DWELL'
'with' acts as a link.
(Other definitions for dwell that I've seen before include "Abide, reside" , "Hang out" , "Settle" , "Exist (within)" , "Reside - linger" .)