Lois ran to store (4)
I believe the answer is:
silo
'to store' is the definition.
(a store of crops)
'lois ran' is the wordplay.
'ran' indicates anagramming the letters (letters have run around).
'lois' is an anagram of 'SILO'.
(Other definitions for silo that I've seen before include "Tower for storing grain" , "Grain store; missile site" , "Launch site" , "Missile pit" , "Store for grain or fodder" .)