Lois ran to the store (4)
I believe the answer is:
silo
'the store' is the definition.
(a store of crops)
'lois ran' is the wordplay.
'ran' indicates an anagram (letters have run around).
'lois' with letters rearranged gives 'SILO'.
'to' acts as a link.
(Other definitions for silo that I've seen before include "Farm grain storer" , "Tower for storing grain" , "Cylindrical storage tower" , "Grain storage area" , "Underground chamber for a missile" .)