Lois ran to the store (4)
I believe the answer is:
silo
'the store' is the definition.
(a store of crops)
'lois ran' is the wordplay.
'ran' is an anagram indicator (letters have run around).
'lois' anagrammed gives 'SILO'.
'to' is the link.
(Other definitions for silo that I've seen before include "Farm grain storer" , "Tower for storing grain" , "Cylindrical storage tower" , "Grain storage area" , "Underground chamber for a missile" .)