Look spent and ruined (6,2)

I believe the answer is:

loused up

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'ruined' is the definition.
I know nothing about this answer so I can't judge whether this works.

'look spent' is the wordplay.
'look' becomes 'lo' (archaic exclamation meaning 'look!').
'spent' becomes 'used-up' ('use up' can be a synonym of 'spend').
'lo'+'usedup'='LOUSED UP'

'and' acts as a link.

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I've seen this clue in The Guardian.

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