Loose woman in the family losing face (5)
I believe the answer is:
untie
'loose' is the definition.
(loose can mean to untie or unleash)
'woman in the family losing face' is the wordplay.
'woman in the family' becomes 'auntie' (I've seen this before).
'losing face' means to remove the first letter.
'auntie' with its first letter taken off is 'UNTIE'.
(Other definitions for untie that I've seen before include "get rid of bonds" , "Release, loosen" , "Disconnect; release" , "Loosen ropes or knots" , "Release (knots)" .)