Lots of wiggle room is an evolutionary trial (6)
I believe the answer is:
scopes
'lots of wiggle' is the definition.
The definition and answer can be both man-made objects as well as being plural nouns.
Perhaps there's an association between them I don't understand?
'room is an evolutionary trial' is the wordplay.
'room' becomes 'scope' (as in scope or room for manoeuvre).
'is an evolutionary trial' becomes 's' (I can't justify this - if you can you should believe this answer much more).
'scope'+'s'='SCOPES'
Can you help me to learn more?
(Other definitions for scopes that I've seen before include "Optical instruments" , "Assesses" , "Sizes or ranges of subject or topics covered" , "Ranges of activity" , "These small instruments" .)