Made to suffer in wicked college life (7)
I believe the answer is:
academe
'college life' is the definition.
(I've seen this in another clue)
'made to suffer in wicked' is the wordplay.
'to suffer' is an anagram indicator (I've seen 'suffering' mean this).
'in' means one lot of letters goes inside another.
'wicked' becomes 'ace' (ace can informally mean very good).
'made' with letters rearranged gives 'adem'.
'adem' put into 'ace' is 'ACADEME'.
(Other definitions for academe that I've seen before include "Scholarly life" , "The scholarly world" , "university life" , "place of learning" , "The world of education" .)