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Major artery (5)

Ross

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7

aorta

'major artery' is the definition.
(I've seen this before)

This is all the clue.

(Other definitions for aorta that I've seen before include "Main artery from heart" , "Large blood-vessel" , "Principal artery" , "Bloody channel" , "Main artery of body" .)

I've seen this clue in the Evening Standard, the LA Times, the USA Today, the Universal, The Telegraph, The New York Times, the Sydney Morning Herald, the King Feature Syndicate, The Star Tribune, The Mirror and the Penny Press.
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