Make one’s home delightful at the outset? We will (5)
I believe the answer is:
dwell
'make one's home' is the definition.
(synonyms)
'delightful at the outset? we will' is the wordplay.
'at the outset?' suggests taking the first letters (I've seen 'at the outset' mean this (the outset is the beginning)).
'will' becomes 'll' (contracted form, as in 'he'll' - 'he will').
The first letter of 'delightful' is 'd'.
'd'+'we'+'ll'='DWELL'
(Other definitions for dwell that I've seen before include "Focus attention (on)" , "Remain" , "Reside - linger" , "Lodge" , "Harp" .)