Make runs: twenty (5)
I believe the answer is:
score
This clue could be a double definition.
'make' is the first definition.
(I know that make can be written as score)
'runs twenty' is the second definition.
'score' can be an answer for 'twenty' (I've seen this in another clue). I'm unsure of the 'runs' bit.
Can you help me to learn more?
(Other definitions for score that I've seen before include "Notch; twenty" , "Tally; 20" , "Grade; twenty" , "Mark; twenty" , "Musical composition in written form" .)