Malice, venom (5)
I believe the answer is:
spite
I believe this is a double definition.
'malice' is the first definition.
(I know that spite is a type of malice)
'venom' is the second definition.
(I know that venom can be written as spite)
(Other definitions for spite that I've seen before include "Desire to intentionally and maliciously hurt or offend" , "animosity" , "Bitchiness or malice" , "Rancour" , "Hatred" .)