Man may accommodate one, initially inviting obloquy (8)
I believe the answer is:
islander
'man may accommodate one' is the definition.
(resident of the Isle of Man)
'initially inviting obloquy' is the wordplay.
'initially' suggests taking the first letters.
'obloquy' becomes 'slander' (slander is a kind of obloquy).
The initial letter of 'inviting' is 'i'.
'i'+'slander'='ISLANDER'
(Other definitions for islander that I've seen before include "Samoan, Sardinian, Sumatran etc" , "Rum person perhaps" , "Manxman, maybe," , "one from Jersey, perhaps" , "Native of Bali, perhaps" .)