Man of the world, wretch regularly visiting area of London (9)
I believe the answer is:
earthling
'man of the world' is the definition.
(someone from Earth)
'wretch regularly visiting area of london' is the wordplay.
'regularly' means one should take alternating letters (regularly take one letter, leave next etc.).
'visiting' is an insertion indicator.
'area of london' becomes 'Ealing' (Ealing is an area of London).
The alternate letters of 'wretch' are 'rth'.
'rth' inserted within 'ealing' is 'EARTHLING'.
(Other definitions for earthling that I've seen before include "Man of the world" , "Human being (sci-fi)" , "sci-fi character" , "man so to be called from space?" .)