Manual rewritten for graduate (6)
I believe the answer is:
alumna
'for graduate' is the definition.
(term for a female graduate)
'manual rewritten' is the wordplay.
'rewritten' is an anagram indicator.
'manual' is an anagram of 'ALUMNA'.
(Other definitions for alumna that I've seen before include "She studied" , "Harvard graduate" , "Female former pupil" , "Manual (anag) - old girl" , "Female graduate" .)