Married woman in Madrid (6)
I believe the answer is:
senora
'married woman in madrid' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for senora that I've seen before include "Foreign lady; reason (anag.)" , "A married woman in Spain - stands to reason" , "Reason with a Spanish woman, probably married" , "Mrs or madam (Spanish)" , "Lady of Spain" .)