Massage skin regularly each day (5)
I believe the answer is:
knead
'massage' is the definition.
(I know that massage can be written as knead)
'skin regularly each day' is the wordplay.
'regularly' means one should take alternating letters (regularly take one letter, leave next etc.).
'each' becomes 'ea' (abbreviation).
'day' becomes 'd' (abbreviation for day).
The alternate letters of 'skin' are 'kn'.
'kn'+'ea'+'d'='KNEAD'
(Other definitions for knead that I've seen before include "Work (dough) into mass" , "Somehow work in" , "Work (dough/clay)" , "Work together" , "Massage with hands" .)