Mean nurse to support home (6)
I believe the answer is:
intend
'mean' is the definition.
('intend' can be a synonym of 'mean')
'nurse to support home' is the wordplay.
'nurse' becomes 'tend' (I've seen this before).
'to support' means one lot of letters go next to another.
'home' becomes 'in' ('he's home' can mean 'he's in'**).
'tend' put after 'in' is 'INTEND'.
(Other definitions for intend that I've seen before include "Aim, plan" , "Mean; aim" , "Plan, propose" , "Have as purpose or plan" , "Mean (to do something)" .)