Meat and bone to pick (4)
I believe the answer is:
beef
I believe this clue is a double definition.
'meat' is the first definition.
(beef is a kind of meat)
'bone to pick' is the second definition.
(I've seen this in another clue)
'and' acts as a link.
(Other definitions for beef that I've seen before include "Grumble over cattle meat?" , "Grouse - meat" , "Complaint; strength" , "it's unacceptable for vegetarian" , "Meat of the cow" .)