Meat course almost ruined by this wine (9)
I believe the answer is:
lambrusco
'this wine' is the definition.
(I've seen this before)
'meat course almost ruined' is the wordplay.
'meat' becomes 'lamb' (lamb is a kind of meat).
'almost' means to remove the last letter (most of the word but not all of it).
'ruined' is an anagram indicator.
'course' with its final letter taken off is 'cours'.
'cours' anagrammed gives 'rusco'.
'lamb'+'rusco'='LAMBRUSCO'
'by' is the link.
(Other definitions for lambrusco that I've seen before include "Type of Italian wine" , "Medium sweet, semi-sparkling Italian red or white wine" , "Sparkling Italian wine" .)