Microbes of some danger to a titled female (5)
I believe the answer is:
germs
'microbes of some danger' is the definition.
'germs' can be an answer for 'microbes' ('germ' can be a synonym of 'microbe'). I am unsure of the 'of some danger' bit.
'a titled female' is the wordplay.
'a titled' becomes 'ger' (I can't justify this - if you can you should believe this answer much more).
'female' becomes 'Ms.' (Ms. is an example).
'ger'+'ms'='GERMS'
'to' acts as a link.
Can you help me to learn more?
(Other definitions for germs that I've seen before include "Seeds; microbes" , "sprouts" , "Bacteria" , "Starts" , "Causes of disease" .)