Most inconsiderate, pathetic men tease endlessly (7)
I believe the answer is:
meanest
'most inconsiderate' is the definition.
'pathetic men tease endlessly' is the wordplay.
'pathetic' indicates an anagram (a pathetically bad ordering of the letters).
'endlessly' means to remove the last letter.
'men'+'tease'='mentease'
'mentease' with its last letter removed is 'menteas'.
'menteas' is an anagram of 'MEANEST'.
(Other definitions for meanest that I've seen before include "Most miserable" , "Most stingy and least generous" , "Most cruel" , "ultimate in shabbiness?" , "of least value" .)