My work I initially accepted with an eye disorder (6)
I believe the answer is:
myopia
'an eye disorder' is the definition.
'myopia' can be an answer for 'disorder' (myopia is a kind of health problem). I am not sure about the 'an eye' bit.
'my work i initially accepted' is the wordplay.
'work' becomes 'op' (abbreviation for opus).
'initially' says to take the initial letters.
The initial letter of 'accepted' is 'a'.
'my'+'op'+'i'+'a'='MYOPIA'
'with' is the link.
Can you help me to learn more?
(Other definitions for myopia that I've seen before include "Near-sightedness" , "Condition of short sightedness" , "Lack of insight" , "complaint" , "Seeing problem" .)