Neglects untidy regions (7)
I believe the answer is:
ignores
'neglects' is the definition.
('ignore' can be a synonym of 'neglect')
'untidy regions' is the wordplay.
'untidy' is an anagram indicator.
'regions' with letters rearranged gives 'IGNORES'.
(Other definitions for ignores that I've seen before include "cuts" , "Cold shoulders" , "Shrugs off" , "Intentionally disregards" , "Runs away from" .)