Noel times strangely significant event (9)
I believe the answer is:
milestone
'significant event' is the definition.
(I've seen this in another clue)
'noel times strangely' is the wordplay.
'strangely' is an anagram indicator.
'noel'+'times'='noeltimes'
'noeltimes' is an anagram of 'MILESTONE'.
(Other definitions for milestone that I've seen before include "Pillar" , "Significant developmental stage" , "Wayside indicator" , "Significant event or stage - a measure" , "Important stage (reached)" .)