Nothing in Manila (3)
I believe the answer is:
nil
'nothing' is the definition.
(eg nil is zero in football)
'in manila' is the wordplay.
'in' indicates the answer is hidden within the clue.
'NIL' is hidden in the letters of 'manila'.
(Other definitions for nil that I've seen before include "0" , "Nothing, zero" , "Nothing, zilch" , "Score of nought" , "Non-existent" .)