Of sound offspring in charge (5)
I believe the answer is:
sonic
'of sound' is the definition.
(I've seen this in another clue)
'offspring in charge' is the wordplay.
'offspring' becomes 'son' (male offspring).
'in charge' becomes 'ic' (abbreviation for 'in charge').
'son'+'ic'='SONIC'
(Other definitions for sonic that I've seen before include "Relating to the speed of sound" , "Hedgehog" , "Sort of boom" , "Using waves" , "of noise" .)