Often oddly neglected around fashionable Nice (4)
I believe the answer is:
fine
'nice' is the definition.
(thesaurus)
'often oddly neglected around fashionable' is the wordplay.
'oddly neglected' means one should take alternating letters.
'around' indicates putting letters inside.
'fashionable' becomes 'in' ('in' can be similar in meaning to 'fashionable').
The alternating letters of 'often' are 'fe'.
'fe' going around 'in' is 'FINE'.
(Other definitions for fine that I've seen before include "Sheer or excellent" , "Money paid as penalty" , "Very high quality money penalty" , "Excellent kind of monetary penalty" , "Dry and sunny" .)