Once again arranges holiday locations (7)
I believe the answer is:
resorts
'holiday locations' is the definition.
'once again arranges' is the wordplay.
'once again' becomes 're' (I've seen this in other clues).
'arranges' becomes 'sorts' (I've seen this before).
're'+'sorts'='RESORTS'
(Other definitions for resorts that I've seen before include "Holiday towns" , "Holiday places" , "Brings into play: getaway spots" , "places for holidays" , "Haunts" .)