Opening broken relic's hollow cavities (10)
I believe the answer is:
ventricles
'hollow cavities' is the definition.
'ventricles' can be an answer for 'cavities' (ventricle is a kind of cavity). I'm not sure about the 'hollow' bit.
'opening broken relic's' is the wordplay.
'opening' becomes 'vent' (vent is a kind of opening).
'broken' indicates an anagram.
'relics' is an anagram of 'ricles'.
'vent'+'ricles'='VENTRICLES'
Can you help me to learn more?
(Another definition for ventricles that I've seen is " Chambers".)