Opposed to carrying on with no restrictions (4)
I believe the answer is:
agin
'opposed' is the definition.
(I've seen this before)
'to carrying on with no restrictions' is the wordplay.
'to' becomes 'ag' (I can't justify this - if you can you should give a lot more credence to this answer).
'carrying on' becomes 'continuing' ('continue' can be a synonym of 'carry on').
'with no restrictions' indicates the central letters.
The middle of 'continuing' is 'in'.
'ag'+'in'='AGIN'
Can you help me to learn more?
(Other definitions for agin that I've seen before include "Hostile to" , "Dialect form of against" , "Opposed to local" , "Not a fan of" , "Not in favour of" .)