Opposed to once more going to street (7)
I believe the answer is:
against
'opposed to' is the definition.
(I've seen this before)
'once more going to street' is the wordplay.
'once more' becomes 'again' (synonyms).
'going to' says to put letters next to each other.
'street' becomes 'st'.
'again'+'st'='AGAINST'
(Other definitions for against that I've seen before include "close by" , "Not favouring" , "Disapproving of" , "Opposite to" , "In opposition to" .)