Opposed to, one learned, darn it! (8)
I believe the answer is:
confound
'one learned darn it' is the definition.
I can't judge whether this definition defines the answer.
'opposed to' is the wordplay.
'opposed' becomes 'con' (I've seen this in another clue).
'to' becomes 'found' (I can't justify this - if you can you should believe this answer much more).
'con'+'found'='CONFOUND'
Can you help me to learn more?
(Other definitions for confound that I've seen before include "Surprise; defeat (plan)" , "Bewilder" , "Mix up" , "Defeat (a plan or hope)" , "Prove wrong; confuse" .)