Pariah state is expelling six in breach of protocol? (9)
I believe the answer is:
isolation
'pariah state' is the definition.
(state of being made a pariah)
'is expelling six in breach of protocol?' is the wordplay.
I cannot really understand how this works, but
'is' is present in the answer.
'of' could be 'o' and 'o' is found in the answer.
This explanation may well be incorrect...
(Other definitions for isolation that I've seen before include "Seeking seclusion" , "Separation - solitude" , "Quarantine; solitude" , "Detachment" , "Separation, solitariness" .)