Specialised hospital takes on delicate case (5)
I believe the answer is:
niche
'specialised' is the definition.
(I've seen this before)
'hospital takes on delicate case' is the wordplay.
'hospital' becomes 'h' (abbreviation for hospital on maps).
'takes' indicates putting letters inside (take can mean to capture or invade).
'on delicate case' becomes 'nice' (I can't justify this - if you can you should believe this answer much more).
'h' inserted inside 'nice' is 'NICHE'.
(Other definitions for niche that I've seen before include "ideal position" , "somewhere comfortable" , "hole" , "Shallow recess in a wall" , "Speciality" .)