Part of hands holding small book (6)
I believe the answer is:
psalms
'book' is the definition.
(I've seen this before)
'part of hands holding small' is the wordplay.
'part of hands' becomes 'palms' ('palm' is part of 'hand').
'holding' means one lot of letters goes inside another.
'small' becomes 's' (abbreviation - e.g. clothes size).
'palms' going around 's' is 'PSALMS'.
(Other definitions for psalms that I've seen before include "Holy songs" , "in the Bible?" , "Religious songs" , "They're heard in church" , "Move fast, noisily" .)