Pick house in Channel Islands, by church (6)
I believe the answer is:
choice
'pick' is the definition.
('choice' can be a synonym of 'pick')
'house in channel islands by church' is the wordplay.
'house' becomes 'ho' (abbreviation for house).
'in' means one lot of letters goes inside another.
'channel islands' becomes 'ci'.
'by' says to put letters next to each other.
'church' becomes 'ce' (abbreviation for Church of England).
'ho' inserted into 'ci' is 'choi'.
'choi'+'ce'='CHOICE'
(Other definitions for choice that I've seen before include "Variety" , "Preference" , "Act of selection" , "Superior - selection" , "of superior quality" .)