Picture one game differently (5)
I believe the answer is:
image
'picture' is the definition.
(I know that picture can be written as image)
'one game differently' is the wordplay.
'one' becomes 'i' (Roman numeral).
'differently' is an anagram indicator.
'game' is an anagram of 'mage'.
'i'+'mage'='IMAGE'
(Other definitions for image that I've seen before include "Purplish pigment; pool" , "Simulacrum" , "public perception" , "Metaphor; figure" , "Public persona" .)