Place with comfort and charm (6)
I believe the answer is:
please
'charm' is the definition.
'place with comfort' is the wordplay.
'place' becomes 'pl' (abbreviation used in postal addresses).
'with' means one lot of letters go next to another.
'comfort' becomes 'ease' (synonyms).
'pl'+'ease'='PLEASE'
'and' acts as a link.
(Other definitions for please that I've seen before include "'Delight, gratify (6)'" , "(Word used in) asking or accepting politely" , "Delight; amuse" , "Entertain" , "See pal (anag) -- charm" .)