Plant in rather isolated situation, initially (4)
I believe the answer is:
iris
'plant' is the definition.
'in rather isolated situation initially' is the wordplay.
'initially' indicates taking the first letters.
The initial letters of 'in rather isolated situation' is 'IRIS'.
(Other definitions for iris that I've seen before include "Goddess of the rainbow in the eye" , "Part of the eye, usually brown or blue" , "Greek goddess of the rainbow" , "Eye part or attractive flower" , "Flower - girl's name" .)