Pointed end of a lancet, I presume (3)
I believe the answer is:
tip
'pointed end' is the definition.
(I've seen this before)
'of a lancet i presume' is the wordplay.
'of' says the answer is hidden in the clue.
'TIP' is hidden in the letters of 'lancet i presume'.
(Other definitions for tip that I've seen before include "Topple; advice" , "End; piece of advice" , "Hint, suggestion" , "Indication of potential opportunity" , "Gratuity; rubbish-dump" .)