Pointedly ignore friends in the centre? Charming! (4)
I believe the answer is:
cute
'charming' is the definition.
(I've seen this before)
'pointedly ignore friends in the centre?' is the wordplay.
'pointedly ignore' becomes 'cut' (cut can mean to ignore someone when meeting them).
'in the centre?' indicates the central letters (I've seen 'in the centre' mean this).
The central letter of 'friends' is 'e'.
'cut'+'e'='CUTE'
(Other definitions for cute that I've seen before include "Taking" , "Fly" , "Attractive or ingenious" , "Astute - lovely" , "Daintily pleasing" .)