Police officers former PM upset (6)
I believe the answer is:
dismay
'upset' is the definition.
(dismay can mean to upset)
'police officers former pm' is the wordplay.
'police officers' becomes 'DIs' (detective inspectors).
'former pm' becomes 'May' (Theresa May former prime minister).
'dis'+'may'='DISMAY'
(Other definitions for dismay that I've seen before include "Alarm, distress" , "Consternation, distress" , "trouble" , "Feeling of surprise and discouragement" , "Affright" .)