Poor at painting, I strain badly and twitch (10)
I believe the answer is:
inartistic
'poor at painting i strain badly and twitch' is the definition.
I can't tell whether this definition defines the answer.
'i strain badly and twitch' is the wordplay.
'badly' indicates an anagram (letters in the wrong order).
'and' says to put letters next to each other.
'twitch' becomes 'tic' (tic is a kind of twitch).
'strain' with letters rearranged gives 'nartis'.
'i'+'nartis'+'tic'='INARTISTIC'
Can you help me to learn more?
(Another definition for inartistic that I've seen is " Lacking creative talent; intact iris (anagram)".)